In this Series, we reviewed evidence regarding policy or service interventions to improve primary-care quality in LMICs and situated these within a conceptual framework that reflects on how each ...

We included 15 trials (N=100 952). Compared with placebo, SGLT2 inhibitors reduced the risk of first hospitalisation for heart failure by 29% in patients with heart failure (hazard ratio [HR] 0·71 [95 ...

Many patients experience long-lasting health problems after COVID-19. The study aimed to assess 3-year trajectories of a comprehensive set of patient-reported outcome measures (PROMs) in patients ...

The thymus functions as the primary lymphoid organ responsible for the generation of T cells and plays a crucial role in preventing autoimmune reactions by eliminating autoreactive cells before ...

11 case studies have been published regarding phage therapy in pneumology, involving 16 patients with difficult-to-treat respiratory infections (table 1). 7–17 Seven patients had cystic fibrosis, and ...

Vaccines have had a major impact on the control of infectious disease, most recently by helping to combat the COVID-19 pandemic. Prophylactic cancer vaccines have prevented several malignancies by ...

Interstitial lung abnormalities (ILAs) are parenchymal lung changes found on high-resolution CT. In routine use of high-resolution CT, non-specific findings are frequently reported, which has prompted ...

The correspondence of Joan B Soriano and Alberto Ruano-Ravina deserves timely praise, highlighting the threat that predatory ...

The convergence of multiple crises—including the COVID-19 pandemic, geopolitical fragmentation, climate shocks, digital disruption, and economic precarity—has exposed the fragility and limitations of ...

Variation in PICU mortality by ethnicity and area-level deprivation highlights the importance of further investigation into ...

Public trust in scientific integrity is eroded by the politicisation of institutions under Donald Trump's US presidency. The implications extend far beyond American borders, striking at the core of ...

The Non-communicable Diseases Risk Factor Collaboration (NCD-RisC) estimated that 828 million people worldwide aged 18 years or older had diabetes in 2022—considerably more than estimates of the ...